Service: Shuttle + Pullman Bus Tica Bus (1st Class) Journey (4 days): Departure from Antigua to Guatemala City: 9AM Departure from Guatemala City to Salvador (night at the hotel not included): 2PM Departure from Salvador (D+1) to Managua, Nicaragua (night at the hotel not included): 5AM Departure from Managua, Nicaragua (D+2) to Costa Rica (night at the hotel not included): 6AM Departure from Costa Rica (D+3) to Panama: 12PM Arrival in Panama at 11PM.